Lahiri, Indrajit, Dr

Dr Indrajit Lahiri

School of Biosciences

Lecturer in Electron Microscopy

i.lahiri@sheffield.ac.uk
+44 114 222 20035

D14A, Firth Court

Full contact details

Dr Indrajit Lahiri
School of Biosciences
D14A
Firth Court
Western Bank
Sheffield
S10 2TN

Profile

2022 - present: Lecturer in Electron Microscopy, �� of Sheffield

2019-2022: Assistant Professor, IISER Mohali, India

2015-2019: Postdoctoral Researcher, �� of California, San Diego, USA

2014-2015: Postdoctoral Researcher, Harvard ��, USA

2008-2014: PhD, State �� of New York at Albany, USA

Research interests: We study the essential processes of genome replication, repair and compaction in eukaryotic parasites belonging to the phylum Apicomplexa.
Apicomplexans cause deadly diseases like malaria (Plasmodium sp.) and toxoplasmosis (Toxoplasma sp.). These parasites affect over 200 million people worldwide each year. Our interest lies in understanding how apicomplexans carry out DNA transactions within the context of their host - specifically how these processes occur in an organelle called the 'apicoplast'. To answer this question we use electron cryomicroscopy, fast enzyme kinetics, next-generation DNA sequencing and associated biochemical and biophysical techniques.

Publications

Stevenson SR, Tzokov SB, Lahiri I, Ayscough KR & Bullough PA (2025) . Structure.
Sarsam RD, Xu J, Lahiri I, Gong W, Li Q, Oh J, Zhou Z, Hou P, Chong J, Hao N , Li S et al (2024) . Proceedings of the National Academy of Sciences, 121(3), e2314245121.
Karasmanis EP, Reimer JM, Kendrick AA, Nguyen KHV, Rodriguez JA, Truong JB, Lahiri I, Reck-Peterson SL & Leschziner AE (2023) . Nature Structural & Molecular Biology, 30(9), 1357-1364.
Kumari A, Yadav A & Lahiri I (2022) . Biochemistry, 61(21), 2319-2333.
Bakker SE, Bergeron J, Bharadwaj A, Bhella D, Bullough P, Chau P-L, Frank RAW, Jakobi AJ, Joseph AP, Kühlbrandt W , Lahiri I et al () . Faraday Discussions, 240, 229-242.

Stevenson SR, Tzokov SB, Lahiri I, Ayscough KR & Bullough PA (2024) , Cold Spring Harbor Laboratory.
Sarsam RD, Xu J, Lahiri I, Gong W, Oh J, Zhou Z, Chong J, Hao N, Li S, Wang D & Leschziner AE (2023) , Cold Spring Harbor Laboratory.
Leschziner A, Karasmanis E, Reimer J, Kendrick A, Rodriguez J, Truong J, Lahiri I & Reck-Peterson S (2022) , Research Square Platform LLC.

Research group

Ms. Anamika Kumari (BBSRC White Rose DTP PhD student)

Dr. Anjali Yadav (Postdoctoral researcher)